The Troubled Brain: Ageing and Dementia

Diseases such as Alzheimer’s or Parkinson’s are devastating neurological conditions that typically occur at old age and lead to systematic dementia and debilitating symptoms. The underlying mechanisms of these diseases are poorly understood. Yet, a striking feature of these conditions is the characteristic pattern of invasion throughout the brain, leading to well-codified disease stages associated with various cognitive deficits and pathologies.

This lecture shows how mathematical modelling can be used to predict dementia’s progression by unravelling some of its universal features.